Fc-binding protein, method for producing said protein, antibody adsorbent using said protein, and method for separating antibody using said adsorbent
US10815289B2 · kind B2 · utility
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2References
8Claims
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Key dates
| Filing date | Jun 24, 2015 |
| Grant date | Oct 27, 2020 |
| Priority date | — |
| Expiry date | Oct 10, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2400/02
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Provided are: an Fc-binding protein having improved stability, particularly to heat and acid; a method for producing the protein; an antibody adsorbent using the protein; and a method for separating the antibodies using the adsorbent. Specifically provided are: an Fc-binding protein having improved stability to heat and acid, achieved by substituting an amino-acid residue in a specific position in the extracellular region of human FcyRIIIa with another specific amino acid; a method for producing the protein; an antibody adsorbent using the protein; and a method for separating the antibodies using the adsorbent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.