Multispecific antigen binding fragments and multispecific antibodies derived therefrom comprising mutant CH1 and CL-kappa domains
US10815310B2 · kind B2 · utility
3Cited by
1References
13Claims
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Key dates
| Filing date | Mar 20, 2017 |
| Grant date | Oct 27, 2020 |
| Priority date | — |
| Expiry date | Mar 20, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/732
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy chain/light chain mispairing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.