Methods for measuring small molecule affinity to cereblon
US10816544B2 · kind B2 · utility
2Cited by
6References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 2, 2018 |
| Grant date | Oct 27, 2020 |
| Priority date | — |
| Expiry date | Feb 2, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A complex comprises a CRBN having a europium-anti-his antibody on the N-terminus of the CRBN, and a Cy5-conjugated small molecule, wherein the Cy5-conjugated small molecule binds the CRBN, and uses thereof for identifying therapeutic compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.