Patent · US Active

Substituted pyridinone-containing trycyclic compounds, and methods using same

US10821103B2 · kind B2 · utility

0Cited by

4References

58Claims

0Family size

Assignee

ARBUTUS BIOPHARMA CORPORATION · CA

Inventors

Laurèn Danielle Bailey · Hatboro, US
Yingzhi Bi · Plainsboro, US
Shuai Chen · Warrington, US
Bruce D. Dorsey · Ambler, US
Dimitar B. Gotchev · King of Prussia, US
Richard J. Holland · Vancouver, CA
Ramesh Kakarla · Doylestown, US
Duyan Nguyen · North Wales, US
Mark Wood · Port Moody, CA

Key dates

Filing date	Nov 3, 2017
Grant date	Nov 3, 2020
Priority date	—
Expiry date	Nov 3, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F9/6561
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention includes substituted pyridinone-containing tricyclic compounds, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infection in a patient. In certain embodiments, the compounds and compositions of the invention inhibit and/or reduce HBsAg secretion.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.