Liquid protein formulations containing thiamine pyrophosphate (TPP)
US10821184B2 · kind B2 · utility
1Cited by
85References
22Claims
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Key dates
| Filing date | Feb 6, 2018 |
| Grant date | Nov 3, 2020 |
| Priority date | — |
| Expiry date | May 31, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous (SC) or intramuscular (IM) injection, rather than by lengthy intravenous infusion. These formulations include low-molecular-weight and/or high-molecular-weight proteins, such as mAbs, and organophosphates. The viscosity of the formulation is significantly reduced by the addition of one or more organophosphates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.