Patent · US Active

Method for producing reagent for antibody detection and use thereof

US10822384B2 · kind B2 · utility

0Cited by
1References
13Claims
0Family size

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Key dates

Filing dateMar 29, 2013
Grant dateNov 3, 2020
Priority date
Expiry dateMar 29, 2033

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/4704
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention provides the following: a method for efficiently producing a reagent for detecting an antibody that specifically binds with an insoluble antigen protein present in a liquid sample; a reagent for antibody detection produced by the production method; and a use of the antibody. In a step for solubilizing an antigen protein, it is possible to efficiently solubilize and recover the antigen protein by using a cationizing agent; therefore, when compared to conventional methods, it is possible to efficiently produce a reagent for detecting an antibody that has bound to multiple antigen protein molecules in a carrier.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.