Virus purification

US10822591B2 · kind B2 · utility

Assignee

• Kentucky BioProcessing, Inc. · US

Inventors

• Leigh Burden · Owensboro, US
• Steven D. Hume · Owensboro, US
• Joshua D. Morton · Evansville, US
• Greg Pogue · Austin, US
• Barry Bratcher · Owensboro, US
• Hugh A. Haydon · Louisville, US
• Carrie A. Simpson · Evansville, US
• Nick Partain · Owensboro, US
• John W. Shepherd · Owensboro, US

Key dates

• Filing date: Jun 11, 2019
• Grant date: Nov 3, 2020
• Expiry date: Jun 11, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2770/40063
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are methods and exemplary compositions associated with virus purification, exemplary aspects of which may include harvesting viral and antigenic substances from source organisms; and a purification platform comprising chemical separation and size-difference separation for the removal of contaminants, debris and impurities from the viral and protein (e.g. antigenic, including influenza hemagglutinin antigens) substances, as well as their concentration and collection.