Materials and methods for controlling vasculogenesis from endothelial colony forming cells
US10828337B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Feb 7, 2018 |
| Grant date | Nov 10, 2020 |
| Priority date | — |
| Expiry date | Mar 7, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L27/3808
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Materials and methods are disclosed for controlling vasculogenesis using building blocks of a collagen matrix and endothelial colony forming cells (ECFC). The building blocks may be isolated by fractionating an acid soluble Type I collagen. The building blocks comprising monomers and/or oligomers may be recombined in desired ratios to alter the matrix microenvironment and to influence ECFC behavior.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.