3-((hetero-)aryl)-alkyl-8-amino-2-oxo-l,3-diaza-spiro-[4.5]-decane derivatives

US10829480B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Sven Kuehnert · Lehrte, DE
• Rene Michael KOENIGS · Erkelenz, DE
• Achim Kless · Aachen, DE
• Anita WEGERT · Aldenhoven, DE
• Paul Ratcliffe · Lanark, GB
• Ruth Jostock · Stolberg, DE
• Thomas KOCH · Stolberg, DE
• Klaus Linz · Rheinbach, DE
• Wolfgang Schroeder · Aachen, DE
• Klaus Schiene · Goldkronach, DE
• Ingo Konetzki · Warthausen, DE

Key dates

• Filing date: Feb 1, 2019
• Grant date: Nov 10, 2020
• Expiry date: Feb 1, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to 3-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.