Patent · US Active

Beta-hairpin peptidomimetics

US10829520B2 · kind B2 · utility

2Cited by

1References

10Claims

0Family size

Assignee

POLYPHOR AG · CH

Inventors

Daniel Obrecht · Amriswil, CH
Anatol Luther · Binzen, DE
Francesca Bernardini · Hésingue, FR
Peter ZBINDEN · Magden, CH
Alexander Lederer · Basel, CH

Key dates

Filing date	Mar 23, 2016
Grant date	Nov 10, 2020
Priority date	—
Expiry date	Mar 23, 2036

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Beta-hairpin peptidomimetics of the general formula (I), and pharmaceutically acceptable salts thereof, with P, T, Q, and optionally L being elements as defined in the description and the claims, have Gram-negative antimicrobial activity to e.g. inhibit the growth or to kill microorganisms such as Klebsiella pneumoniae and/or Acinetobacter baumannii and/or Escherichia coli and/or Pseudomonas aeruginosa. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials.These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.