Systems and methods enabling patch-clamp re-use
US10830758B2 · kind B2 · utility
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26Claims
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Key dates
| Filing date | Aug 9, 2016 |
| Grant date | Nov 10, 2020 |
| Priority date | — |
| Expiry date | Feb 9, 2038 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/0896
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for cleaning patch-clamp glass pipette electrodes that enables their re-use. By immersing pipette tips or planar patch clamp chips into a detergent, followed by rinsing, pipettes and planar patch clamp chips were re-usable at least ten times with little to no degradation in signal fidelity, in experimental preparations ranging from human embryonic kidney cells to neurons in culture, slices, and in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.