Compositions and methods for inducing conformational changes in cereblon and other E3 ubiquitin ligases
US10830762B2 · kind B2 · utility
0Cited by
67References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 27, 2016 |
| Grant date | Nov 10, 2020 |
| Priority date | — |
| Expiry date | Dec 27, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y203/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compositions, therapeutic methods, screening methods, computational methods and biomarkers based upon the elucidation of the interaction among cereblon, its substrates and certain compounds or agents, including small molecules, peptides, and proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.