Simultaneous proton resonance frequency shift thermometry and T1 measurements using a single reference variable flip angle T1 method
US10830853B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 19, 2019 |
| Grant date | Nov 10, 2020 |
| Priority date | — |
| Expiry date | Apr 19, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/4814
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A computer implemented method for measuring T1 in an anatomical region of interest during a dynamic procedure includes acquiring a reference MR image of the anatomical region of interest using a first flip angle. A first set of dynamic MR images of the anatomical region of interest are acquired using a second flip angle. The reference MR image and the first set are used to calculate a reference T1 value for tissue in the anatomical region of interest. During an intervention where the T1 value may change, a second set of dynamic MR images of the anatomical region of interest is acquired using the second flip angle. The reference MR image and the second set are used to calculate an estimated T1 value. The reference T1 value, the estimated T1 value, and the first and second flip angles may then be used to correct the estimated T1 value.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.