Device and method for acquiring a particle present in a sample
US10831156B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 27, 2017 |
| Grant date | Nov 10, 2020 |
| Priority date | — |
| Expiry date | Aug 3, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T7/97
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A device for acquisition of particles present in a sample includes a spatially coherent light source, an optical system, and an image sensor placed in the focal plane of the optical system. The image sensor is configured to capture an intensity image. A computational unit of the device is configured to construct a series of electromagnetic propagation matrices obtained for a plurality of defocusing offsets relative to a plane of focus of the optics. The computational unit is also configured to determine a first average focused electromagnetic matrix for the particles from the series of electromagnetic matrices, identifying at least one of the particles in the first electromagnetic matrix and storing the coordinates of said particle, and determining a second electromagnetic matrix at a distance of focus on a particle identified from the components of the series of electromagnetic matrices having the stored coordinates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.