Manganese-based chelate conjugates for molecular MR imaging
US10835623B2 · kind B2 · utility
1Cited by
15References
43Claims
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Key dates
| Filing date | Aug 12, 2016 |
| Grant date | Nov 17, 2020 |
| Priority date | — |
| Expiry date | Aug 12, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F13/005
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are examples of metal chelating ligands that have high affinity for manganese. The resultant metal complexes can be used as MRI contrast agents, and can be functionalized with moieties that bind to or cause relaxivity change in the presence of biochemical targets.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.