Compounds for imaging Tau protein aggregates

US10835624B2 · kind B2 · utility

Assignees

• AC Immune SA · CH
• LIFE MOLECULAR IMAGING SA · CH

Inventors

• Heiko Kroth · Ecublens, CH
• Jerome Molette · Ferney-Voltaire, FR
• Vincent DARMENCY · Bougy-Villars, CH
• Hanno Schieferstein · Berlin, DE
• Andre Müller · Berlin, DE
• Heribert Schmitt-Willich · Berlin, DE
• Mathias Berndt · Berlin, DE
• Felix Oden · Berlin, DE
• Emanuele Gabellieri · Lausanne, CH

Key dates

• Filing date: Jul 21, 2017
• Grant date: Nov 17, 2020
• Expiry date: Jul 21, 2037

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/2821
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel compounds of the formula (II) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emission Tomography (PET) Imaging.