N-substituted bicyclic lactams, their preparation and their use as pharmaceuticals
US10836742B2 · kind B2 · utility
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5References
25Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 11, 2016 |
| Grant date | Nov 17, 2020 |
| Priority date | — |
| Expiry date | May 30, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This application relates to N-substituted bicyclic lactams of formula (I), compositions comprising them and their uses in the treatment of diseases and conditions in which inhibition of a bromodomain is indicated. For example, the application relates to the N-substituted bicyclic lactams of formula (I) and to their use as bromodomain inhibitors. The present application is also related to the treatment or prevention of proliferative disorders, auto-immune disorders, inflammatory disorders, dermal disorders, and neoplasms, including tumors and/or cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.