Derivatives of amanita toxins and their conjugation to a cell binding molecule
US10836796B2 · kind B2 · utility
8Cited by
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27Claims
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Key dates
| Filing date | Apr 20, 2016 |
| Grant date | Nov 17, 2020 |
| Priority date | — |
| Expiry date | Sep 16, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is related to novel cytotoxic agents, derivatives of Amanita toxins of Formula (I), wherein , -----, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, L, m, n and Q are defined herein, the preparation and the therapeutic uses in the targeted treatment of cancers, autoimmune disorders, and infectious diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.