Modifying messenger RNA stability in plant transformations
US10837024B2 · kind B2 · utility
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Key dates
| Filing date | Feb 29, 2016 |
| Grant date | Nov 17, 2020 |
| Priority date | — |
| Expiry date | Jun 2, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Materials and methods for genome engineering through transient expression of a targeted nuclease are described herein. For example, the methods described herein can include introducing into a cell a messenger RNA (mRNA) that encodes a nuclease targeted to a selected sequence within the cell, where the stability of the mRNA is modified by the addition of untranslated regions (UTRs).
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