Methods of treating cancer using bacteria expressing c-di-AMP

US10842828B2 · kind B2 · utility

Assignee

• THE JOHNS HOPKINS UNIVERSITY · US

Inventors

• William R. Bishai · Baltimore, US
• Ruchi Jain Dey · Baltimore, US
• Bappaditya Dey · Baltimore, US
• Laurene Cheung · Baltimore, US

Key dates

• Filing date: Oct 1, 2018
• Grant date: Nov 24, 2020
• Expiry date: Oct 1, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2039/522
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are methods of treating or preventing cancer in a subject comprising administering to the subject an effective amount of a bacteria comprising and expression vector encoding a di-adenylate cyclase enzyme.