Patent · US Active

Intermediates for the preparation of remifentanil hydrochloride

US10844014B2 · kind B2 · utility

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12Claims
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Key dates

Filing dateOct 25, 2019
Grant dateNov 24, 2020
Priority date
Expiry dateOct 25, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D211/98
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A new intermediate for synthesizing 1-substituted-4-[phenyl(propanoyl)amino]piperidine-4-carbonitrile derivatives is laid open. Specifically set out is a method for use of this intermediate in the preparation of remifentanil. The enclosed shorter process offers a greater yield of products with higher purity as compared to methods reported in the prior art.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.