Anti-CTLA-4 antibodies and uses thereof
US10844137B2 · kind B2 · utility
1Cited by
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20Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 26, 2018 |
| Grant date | Nov 24, 2020 |
| Priority date | — |
| Expiry date | Jul 26, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides antibodies that bind to cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), and methods of use. In various embodiments of the invention, the antibodies are fully human antibodies that specifically bind to CTLA-4. In some embodiments, the antibodies of the invention are useful for inhibiting or neutralizing CTLA-4 activity, thus providing a means of activating T-cells and/or for treating a disease or disorder such as cancer or viral infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.