Polynucleotides encoding biocatalysts and methods for hydroxylation of chemical compounds
US10844358B2 · kind B2 · utility
2Cited by
105References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 20, 2018 |
| Grant date | Nov 24, 2020 |
| Priority date | — |
| Expiry date | Nov 20, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y114/11002
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.