Patent · US Active

Materials and methods for producing endostatin fusion polypeptides in plant cells

US10844392B2 · kind B2 · utility

1Cited by
28References
19Claims
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Key dates

Filing dateJun 3, 2016
Grant dateNov 24, 2020
Priority date
Expiry dateJun 3, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This document provides materials and methods for producing endostatin fusion polypeptides having anti-fibrotic activity. For example, provided herein are fusion polypeptides having an IgG Fc domain and a portion of human endostatin that can form high molecular weight multimers, as well as methods for producing such fusion polypeptides in plant cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.