Self-assembled residence devices and related methods

US10849853B2 · kind B2 · utility

Assignees

• Massachusetts Institute of Technology · US
• The Brigham and Women's Hospital, Inc. · US

Inventors

• Andrew Bellinger · Wellesley, US
• Shiyi Zhang · Shanghai, CN
• Carlo Giovanni Traverso · Newton, US
• Robert S. Langer · Newton, US
• Stacy Mo · Darien, US
• Jiaqi Lin · Somerville, US
• Angela DiCiccio · San Francisco, US
• Dean Liang Glettig · Cambridge, US
• Lowell L. Wood, Jr. · Bellevue, US
• Philip A. Eckhoff · Bellevue, US

Key dates

• Filing date: Jun 11, 2015
• Grant date: Dec 1, 2020
• Expiry date: Jun 11, 2035

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Residence devices as well as their related methods of manufacture and use are generally provided. In some embodiments, a residence device includes a plurality of self-assembling structures that assemble in vivo to form an aggregate structure. Each structure of the plurality of structures includes a first side and a first attachment point that attaches to a second attachment point on another structure of the plurality of structures. The aggregate structure may be sized and shaped to maintain an in vivo position relative to an internal orifice of a subject. The attachment between the first and second attachment points may degrade after a period of time.