Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof
US10849981B2 · kind B2 · utility
0Cited by
15References
126Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 22, 2018 |
| Grant date | Dec 1, 2020 |
| Priority date | — |
| Expiry date | Oct 22, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal. The presently described methods are carried out by comprising administering to the patient a pharmaceutically effective amount of a composition comprising acetaminophen and benzoate-hydrocodone hydrochloride. The composition has reduced side effects when compared with unconjugated hydrocodone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.