In-situ cross-linkable polymeric compositions and methods thereof
US10850003B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 1, 2017 |
| Grant date | Dec 1, 2020 |
| Priority date | — |
| Expiry date | Jun 1, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2400/04
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.