Automated optimization of his bundle pacing for cardiac resynchronization therapy

US10850107B2 · kind B2 · utility

Assignee

• PACESETTER, INC. · US

Inventors

• Wenwen Li · San Jose, US
• Gene A. Bornzin · Simi Valley, US
• Nima Badie · Berkeley, US
• Stuart Rosenberg · Santa Clarita, US
• Luke C. McSpadden · Los Angeles, US
• Kyungmoo Ryu · Palmdale, US

Key dates

• Filing date: Nov 5, 2018
• Grant date: Dec 1, 2020
• Expiry date: Feb 14, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/371
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Systems and methods of performing cardio resynchronization therapy (CRT) on a patient heart include the use of a stimulation system having at least one processor, at least one memory, a pulse generator, a stimulating electrode disposed in proximity to a His bundle of the patient heart, and a sensing electrode adapted to sense electrical activity of the left ventricle (LV) of the patient heart. CRT is provided by applying, using the pulse generator and through the stimulating electrode, a His bundle pacing (HBP) impulse having a first impulse energy. The sensing electrode is then used to measure an LV activation time in response to the HBP impulse. At least one setting of the pulse generator is modified based on the LV activation time such that a subsequent HBP impulse may be provided by the pulse generator via the stimulating electrode using a modified impulse energy.