Synthesis of cerdulatinib

US10851087B2 · kind B2 · utility

Assignee

• Portola Pharmaceuticals, Inc. · US

Inventors

• Anjali Pandey · Fremont, US
• Arvinder Sran · Fremont, US
• Ying Chen · Thousand Oaks, US
• Daniele Poggiali · Lugano, CH
• Tiziano Fumagalli · Lipomo, IT

Key dates

• Filing date: May 3, 2019
• Grant date: Dec 1, 2020
• Expiry date: May 3, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D239/48
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure provides processes for the preparation of cerdulatinib, which is of formula I: or a salt thereof. The disclosure also provides intermediates and processes for the preparation of the intermediates useful in the preparation of cerdulatinib or a salt thereof.