Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents

US10851096B2 · kind B2 · utility

Assignees

• Rutgers, the State University of New Jersey · US
• The Curators of the University of Missouri · US

Inventors

• William J. Welsh · New Brunswick, US
• Raymond Birge · New York, US
• Vladyslav Kholodovych · New Brunswick, US
• Youyi Peng · Plainsboro, US
• Thomas Walter Comollo · New Brunswick, US
• Stanley G. Kimani · New Brunswick, US
• Kamlendra Singh · Columbia, US

Key dates

• Filing date: Jun 16, 2017
• Grant date: Dec 1, 2020
• Expiry date: Jun 16, 2037

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Certain compounds of formula I: I and salts including pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I.