Immunostimulatory plasmids

US10851379B2 · kind B2 · utility

Assignee

• Bayer Animal Health GmbH · DE

Inventors

• Marc Munnes · Erkrath, DE
• Christian Weiss · Leverkusen, DE
• Elisabeth Feldhues · Bensberg, DE
• Romina G. Schauer · Lenexa, US
• Albert Abraham · Shawnee, US
• Andrea Eicker · Rheydt, DE
• Hermann Wehlmann · Wuppertal, DE

Key dates

• Filing date: Apr 25, 2018
• Grant date: Dec 1, 2020
• Expiry date: Apr 25, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2710/16771
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to immunomodulator compositions and methods of use as well as methods of making. The immunomodulator compositions comprise immunostimulatory plasmids, or DNA sequence, capable of eliciting an immune response in a recipient subject. Further, the immunostimulatory plasmids, or DNA sequence, do not contain antibiotic resistance coding sequence to help reduce the potential of horizontal transfer of antibiotic resistance in a population.