Coaxial needle for fabricating a multi scale, multi layer blood vessel or vascular network employing 3D bioprinting
US10857260B2 · kind B2 · utility
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1References
23Claims
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Key dates
| Filing date | Jan 8, 2018 |
| Grant date | Dec 8, 2020 |
| Priority date | — |
| Expiry date | Jan 7, 2039 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29C64/135
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A coaxial needle having two or more passageways for forming a biomimetic bioprinted blood vessel tubular construct. The coaxial needle has an external needle passageway and an internal needle passageway separated by an internal barrier, and having a nozzle at an end thereof. A bioink is provided flowable through the external needle passageway and a crosslinking solution is provided flowable through the internal needle passageway. The crosslinking solution contacts the bioink as the crosslinking solution and bioink exit the nozzle thereby forming a tubular blood vessel construct.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.