Method for synthesizing iodo- or astatoarenes using diaryliodonium salts

US10858306B2 · kind B2 · utility

Assignees

• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
• UNIVERSITE DE NANTES · FR
• UNIVERSITE D'ANGERS · FR
• The Government of the United States of American, as represented by the Secretary, Department of Health and Human Services · US

Inventors

• Francois Guerard · Paris, FR
• Jean-Francois Gestin · Nantes, FR
• Martin W. Brechbiel · Annandale, US
• Yong Sok Lee · Fairfax Station, US

Key dates

• Filing date: Apr 9, 2020
• Grant date: Dec 8, 2020
• Expiry date: Apr 9, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/05
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.