Water-soluble myosin 2 inhibitors for the treatment of neurological, neuropathic or psychiatric diseases
US10858357B2 · kind B2 · utility
3Cited by
0References
22Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jan 27, 2017 |
| Grant date | Dec 8, 2020 |
| Priority date | — |
| Expiry date | Jan 27, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to highly soluble, non-fluorescent and photostable myosin inhibitors; especially, for in vivo inhibition of the ATPase activity of neuronal non-muscle myosin 2 of formula (II): wherein Q1, Q2, Q3, Q4, R1, R2, R4 and R5 are as defined in claim 1. The invention also relates to pharmaceutical compositions or medicaments comprising the compounds of the invention and processes for manufacturing these compounds and their intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.