Patent · US Active

SGC stimulators

US10858363B2 · kind B2 · utility

2Cited by

9References

10Claims

0Family size

Assignee

Cyclerion Therapeutics, Inc. · US

Inventors

Glen Robert Rennie · Somerville, US
Rajesh R. Iyengar · Newton, US
Thomas Wai-Ho Lee · Lexington, US
Takashi Nakai · Newton, US
Ara Mermerian · Somerville, US
Lei Jia · San Diego, US
G-Yoon Jamie Im · Cambridge, US
Paul Allan Renhowe · Sudbury, US
Joon Jung · Newton, US
Peter Germano · Newton, US
Karthik Iyer · Cambridge, US
Timothy Claude Barden · Salem, US
Kim Tang · Belmont, US

Key dates

Filing date	Feb 12, 2019
Grant date	Dec 8, 2020
Priority date	—
Expiry date	Feb 12, 2039

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or an upregulation of the NO pathway is desirable. The compounds are of Formula I:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.