Process for the preparation of deoxycholic acid

US10858387B2 · kind B2 · utility

Assignee

• Glenmark Life Sciences Limited · IN

Inventors

• Ranjeet Nair · Mumbai, IN
• Shekhar Bhaskar Bhirud · Mumbai, IN
• Nandkumar Gaikwad · Navi Mumbai, IN
• Sharad Gore · Kalyan-Dombivli, IN
• Rajendra Jagdhane · Pune, IN
• Sandip Tukaram Gadge · Pune, IN
• Sukumar Sinha · Mumbai, IN

Key dates

• Filing date: May 21, 2018
• Grant date: Dec 8, 2020
• Expiry date: May 21, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J41/0061
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides a process for preparation of deoxycholic acid or salt thereof; the process comprises the steps of reacting the compound of formula II to obtain a compound of formula III; the compound of formula III is converted to a compound of formula IV and the compound of formula IV is converted to deoxycholic acid. The present invention also provides a process for the purification of deoxycholic acid or salt thereof.