Transgenic plants expressing a variable domain of a heavy chain antibody (VHH) that binds to a sphingolipid of a fungus

US10858666B2 · kind B2 · utility

Assignee

• BIOTALYS NV · BE

Inventors

• Peter Verheesen · Mariakerke, BE
• Jan Geerinck · Puivelde, BE
• João Filipe Veloso Vieira · Biggenden, AU
• Marnix Peferoen · Bellem, BE
• Inge Elodie Van Daele · Wondelgem, BE

Key dates

• Filing date: Nov 5, 2015
• Grant date: Dec 8, 2020
• Expiry date: Nov 5, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/569
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

This disclosure relates to a transgenic plant or plant tissue or plant cell comprising at least one polynucleotide encoding a polypeptide comprising a variable domain of a heavy-chain antibody (VHH) specifically binding to a sphingolipid of a fungus. This disclosure further relates to a method for protecting at least part of a plant, plant tissue or plant cell from an infection with a plant pathogen, for inhibiting the growth of a plant pathogen on at least part of a plant, plant tissue or plant cell, or for increasing pathogen resistance of at least part of a plant, plant tissue or plant cell.