Drug delivery systems comprising solid solutions of weakly basic drugs
US10864166B2 · kind B2 · utility
8Cited by
3References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 6, 2013 |
| Grant date | Dec 15, 2020 |
| Priority date | — |
| Expiry date | Mar 18, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to pharmaceutical compositions and dosage forms comprising TPR beads, wherein said TPR beads comprise a solid dispersion of at least one active pharmaceutical ingredient in at least one solubility-enhancing polymer, and a TPR coating comprising a water insoluble polymer and an enteric polymer, wherein the active pharmaceutical ingredient comprises a weakly basic active pharmaceutical ingredient having a solubility of not more than 100 μg/mL at pH 6.8.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.