Patent · US Active

Combination of immunotherapy with local chemotherapy for the treatment of malignancies

US10864180B2 · kind B2 · utility

1Cited by

1References

9Claims

0Family size

Assignee

THE JOHNS HOPKINS UNIVERSITY · US

Inventors

Dimitrios Mathios · Baltimore, US
Betty M. Tyler · Baltimore, US
Drew M. Pardoll · Silver Spring, US
Henry Brem · Baltimore, US
Michael Lim · Wolverhampton, GB

Key dates

Filing date	Apr 22, 2016
Grant date	Dec 15, 2020
Priority date	—
Expiry date	Apr 22, 2036

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/505
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The presently disclosed subject matter provides methods, compositions, and kits for the treatment of cancer using a combination treatment comprising a locally administered chemotherapy and an immunotherapeutic agent. The presently disclosed subject matter also provides methods of promoting the combination treatment and instructing a patient to receive the combination treatment are also provided, as well immunotherapeutic, non-immunosuppressive compositions comprising the combination treatment, and methods of using the immunotherapeutic, non-immunosuppressive compositions for treating cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.