Patent · US Active

Modified lipopolysaccharide glycoform and method of use

US10864266B2 · kind B2 · utility

0Cited by

0References

2Claims

0Family size

Assignee

THE TRUSTEES OF PRINCETON UNIVERSITY · US

Inventors

Thomas J. Silhavy · Montgomery, US
Marcin Grabowicz · Princeton, US
Daniel Kahne · Brookline, US
Matthew Lebar · Boston, US
Dorothee Andres · Potsdam, DE

Key dates

Filing date	Nov 21, 2019
Grant date	Dec 15, 2020
Priority date	—
Expiry date	Nov 21, 2039

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/55594
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure generally relates to genetic engineering of bacteria. More particularly, the present disclosure describes genetic engineering of E. coli to create mutant O-antigen ligase, as well as novel lipopolysaccharide molecules resulting from that genetic engineering. Methods for using those novel molecules are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.