Patent · US Active

Heterocyclic compounds useful as modulators of TNF alpha

US10865191B2 · kind B2 · utility

0Cited by
2References
4Claims
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Assignee

Inventors

Key dates

Filing dateAug 2, 2016
Grant dateDec 15, 2020
Priority date
Expiry dateAug 2, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are compounds of Formula (I) or a salt thereof, wherein: A is CR1 or N; B is CR3 or N; D is CR4 or N; L1 is —(CR7R7)m—; L2 is —(CR7R7)n—; and X, Z, R1, R2, R3, R4, R5, and R6 are define herein. Also disclosed are methods of using such compounds as modulators of TNFα, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.