Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
US10865452B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 6, 2016 |
| Grant date | Dec 15, 2020 |
| Priority date | — |
| Expiry date | Apr 6, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A90/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A system for expression-based discrimination of distinct clinical disease states in prostate cancer is provided that is based on the identification of sets of gene transcripts, which are characterized in that changes in expression of each gene transcript within a set of gene transcripts can be correlated with recurrent or non-recurrent prostate cancer. The Prostate Cancer Prognostic system provides for sets of “prostate cancer prognostic” target sequences and further provides for combinations of polynucleotide probes and primers derived there from. These combinations of polynucleotide probes can be provided in solution or as an array. The combination of probes and the arrays can be used for diagnosis. The invention further provides further methods of classifying prostate cancer tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.