EWOD cartridge position sensing when docked in EWOD instrument
US10870114B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 11, 2019 |
| Grant date | Dec 22, 2020 |
| Priority date | — |
| Expiry date | Aug 26, 2039 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0427
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A microfluidic system includes: an electro-wetting on dielectric (EWOD) cartridge having an element array configured to receive liquid droplets, the element array including individual array elements each including array element circuity comprising sensing circuitry that is integrated into the array element circuitry; a microfluidic instrument that is configured to receive the EWOD cartridge and having an electrically conductive locator that is external to the EWOD cartridge; and a control system configured perform electrowetting operations by controlling actuation voltages applied to the element array to perform manipulation operations as to liquid droplets present on the element array. The control system further is configured to read an output from the sensing circuitry, determine a position of the locator relative to the element array based on the output, and determine a misalignment of the EWOD cartridge relative to the microfluidic instrument based on the position of the locator. The control system may adjust a droplet manipulation operation to compensate for the determined misalignment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.