Patent · US Active

Single-chain CD137-receptor agonist proteins

US10870688B2 · kind B2 · utility

0Cited by

0References

15Claims

0Family size

Assignee

APOGENIX AG · DE

Inventors

Christian Gieffers · Dossenheim, DE
Oliver Hill · Neckarsteinach, DE
Meinolf Thiemann · Schriesheim, DE
Tim SCHNYDER · Igersheim, DE

Key dates

Filing date	Apr 17, 2018
Grant date	Dec 22, 2020
Priority date	—
Expiry date	Aug 28, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/74
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are specific CD137 receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a CD137L-associated disease or disorder. The CD137 receptor agonist proteins provided herein comprise three soluble CD137L domains and an Fe fragment. The CD137 receptor agonist proteins are substantially non-aggregating and suitable for therapeuctic, diagnostic and/or research applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.