Patent · US Active

Vessel for growth of biological entities

US10870822B2 · kind B2 · utility

0Cited by
6References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 9, 2015
Grant dateDec 22, 2020
Priority date
Expiry dateMay 18, 2035

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01F29/40221
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

A 5-liter bioreactor vessel enables a substantial increase in the volume of biological media that can be cultivated in the vessel compared to conventional designs. Moreover, when agitated at 1.5× the shaking frequency of a conventional 3-liter bioreactor (i.e., 90 rpm versus 60 rpm), the 5-liter vessel achieves a 19% increase in cell aeration without exceeding the maximum shear stress limit for cell viability. The 5-liter vessel optionally includes a plurality of internal baffles configured to disrupt the liquid vortex and reduce the maximum shear stress transferred to biomedia contained within the vessel.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.