Vessel for growth of biological entities
US10870822B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 9, 2015 |
| Grant date | Dec 22, 2020 |
| Priority date | — |
| Expiry date | May 18, 2035 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01F29/40221
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A 5-liter bioreactor vessel enables a substantial increase in the volume of biological media that can be cultivated in the vessel compared to conventional designs. Moreover, when agitated at 1.5× the shaking frequency of a conventional 3-liter bioreactor (i.e., 90 rpm versus 60 rpm), the 5-liter vessel achieves a 19% increase in cell aeration without exceeding the maximum shear stress limit for cell viability. The 5-liter vessel optionally includes a plurality of internal baffles configured to disrupt the liquid vortex and reduce the maximum shear stress transferred to biomedia contained within the vessel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.