Enzymatic method for preparing glyceryl butyrate

US10870869B2 · kind B2 · utility

Assignee

• South China University of Technology · CN

Inventors

• Yonghua Wang · Suzhou, CN
• Weifei Wang · 流花街道, CN
• Bo Yang · 流花街道, CN
• Dongming Lan · 流花街道, CN
• Fanghua Wang · 流花街道, CN
• Xuehui LI · 流花街道, CN
• Dongqi Zhu · 流花街道, CN
• Daoming Li · 流花街道, CN
• Zhigang Li · Fryeburg, US
• Huayong Chen · Sichuan, CN

Key dates

• Filing date: Nov 8, 2017
• Grant date: Dec 22, 2020
• Expiry date: Nov 8, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y301/01003
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

An enzymatic method for preparing glyceryl butyrate, comprising: (1) carrying out an esterification reaction between n-butyric acid and glycerol using lipase as a catalyst, ethyl acetate and/or ethyl formate as an additive; (2) separating the reaction product, recovering the additive by distillation under reduced pressure to obtain glyceryl butyrate. The invention uses lipase as a catalyst to catalyze the esterification reaction of n-butyric acid and glycerin at normal temperature and normal pressure, reduces the energy consumption of the reaction. Also, the reaction condition is mild, no side reaction happens, and no water-carrying agent is used. In addition, the additive increases the catalytic efficiency of the lipase and the conversion rate of butyric acid.