Patent · US Active

Ovarian neuromodulation and associated systems and methods

US10874455B2 · kind B2 · utility

0Cited by
397References
20Claims
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Key dates

Filing dateAug 2, 2017
Grant dateDec 29, 2020
Priority date
Expiry dateJul 26, 2039

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61B2018/0212
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Methods for treating polycystic ovary syndrome with therapeutic ovarian neuromodulation and associated systems and methods are disclosed herein. Polycystic ovary syndrome can be associated, for example, with a condition including at least one of oligo/amenorrhea, infertility, hirsutism, obesity, metabolic syndrome, insulin resistance, and increased cardiovascular risk profile. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate an ovarian artery of an ovary of a patient. Sympathetic drive in the patient can thereby be reduced in a manner that treats the patient for the polycystic ovary syndrome. Ovarian sympathetic nerve activity can be modulated along afferent and/or efferent pathways. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g., a therapeutic assembly configured to use electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the ovarian nerve.

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