Azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission

US10875829B1 · kind B1 · utility

Assignee

• INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB · SE

Inventors

• Clas Sonesson · Lindome, SE
• Fredrik Pettersson · Handen, SE

Key dates

• Filing date: Nov 17, 2017
• Grant date: Dec 29, 2020
• Expiry date: Nov 17, 2037

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of Formula (I): (I) or an isotope labelled analog thereof, or a pharmaceutically acceptable salt thereof, wherein: each of R1, R2, R3, R6 and R7 represents H or F, R4 represents H or CH3 R5 represents H or C1-C4alkyl, wherein at least two of R1, R2, R3, R6 and R7 represent F, together with at least one pharmaceutically acceptable carrier, excipient and/or diluent.