Process for preparing tetrahydrocarbazole carboxamide compound

US10875843B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Ronald Carrasquillo · Somerville, US
• Peng Geng · Fryeburg, US
• Eric C. Huang · Cranbury, US
• Kishta Katipally · Monmouth Junction, US
• Andrew Lee · Pittsburgh, US
• Boguslaw M. Mudryk · Plainsboro, US
• Xinhua Qian · Flemington, US
• Thomas M. Razler · Yardley, US
• Jianji Wang
• Carolyn S. Wei · Hoboken, US
• Steven R. Wisniewski · New Brunswick, US
• Ye Zhu · Singapore, SG

Key dates

• Filing date: Dec 19, 2017
• Grant date: Dec 29, 2020
• Expiry date: Dec 19, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/88
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed is a process for preparing Compound 8: (8) comprising the step of reacting Compound of 7: (7) wherein R is C1-8 alkyl or benzyl in the presence of a base. Also disclosed are intermediates and processes for preparing the intermediates.