Patent · US Active

Methods and compositions for reducing immunosupression by tumor cells

US10876120B2 · kind B2 · utility

4Cited by

0References

9Claims

0Family size

Assignees

DANA-FARBER CANCER INSTITUTE, INC. · US
The General Hospital Corporation · US

Inventors

Kai W. Wucherpfennig · Brookline, US
Glenn Dranoff · Lexington, US
Penghui Zhou · Quincy, US
Donald Shaffer · Boston, US
Nir Hacohen · Cambridge, US
Harvey Cantor · Boston, US
Diana Alvarez Arias · Midland, US

Key dates

Filing date	Apr 3, 2018
Grant date	Dec 29, 2020
Priority date	—
Expiry date	Aug 14, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/178
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.